Asian stocks fell on Wednesday amid the possibility of Federal Reserve rate cut and fears of a delay in the initial US-China trade deal.
The MSCI index fell 0.33% from its three-month high on Tuesday.
Japan's Nikkei fell 0.35% after touching a one-day high yesterday.
The market lost its profits after a report by US officials on the possibility that the US-China agreement would not be ready for signature at the Chile summit.
On Wall Street, the S&P 500 index hit a new high after good earnings from drug manufacturing such as Merck and Pfizer, before losing 0.08% at the end of trading.
Google parent Alphabet's weak earnings report led the Nasdaq to fall 0.59%.
Expectations of a reduction of 0.25% by federal Reserve emboldened investors. The Fed will set interest rates tonight.